Supplements

Peer-reviewed research concerning supplements, summarized and appraised in plain language with every source cited.

42Studies
42Human studies
2026Most recent
13Countries

Nicotinamide and Pyridoxine Supplementation Enhances Muscle Stem Cell Activity and Muscle Regeneration in Humans: A Randomized Placebo-Controlled Clinical Trial of High Force Eccentric Contraction Recovery in Healthy Young Men.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)2026n = 39 out of 43 enrolled completed the study

RCTHuman

This study tested whether a combination of nicotinamide (a form of vitamin B3) and pyridoxine (vitamin B6) could boost muscle stem cell activity and speed up muscle repair after intense…

Combined creatine and β-hydroxy-β-methylbutyrate supplementation with integral conditioning exercise enhances functional performance and metabolic health in physically active older adults: A randomized controlled crossover trial.

Aging clinical and experimental research2026n = 30

RCTHuman

This study set out to see if combining creatine (a compound stored in muscle that helps regenerate quick energy) and β-hydroxy-β-methylbutyrate (HMB, a muscle-preserving supplement) with exercise could improve mobility…

Exploring the efficacy and safety of a novel standardized ashwagandha (Withania somnifera) root extract (Witholytin®) in adults experiencing high stress and fatigue in a randomized, double-blind, placebo-controlled trial.

Journal of psychopharmacology (Oxford, England)2023

RCTHuman

This study set out to test whether ashwagandha, a traditional herb, could reduce stress and fatigue in overweight or mildly obese adults aged 40-75 who reported high stress and fatigue.…