Peer-reviewed research concerning supplements, summarized and appraised in plain language with every source cited.
This study set out to see if creatine supplements work differently when taken with resistance training versus other types of exercise. It pooled data from 39 trials in healthy men…
This study looked at whether vitamin D changes how well metformin (a common diabetes drug that lowers blood sugar) can bring down prolactin (a pituitary hormone that suppresses testosterone when…
This study set out to compare a micronized form of creatine monohydrate (KleanCREATINE™) with a standard creatine supplement in active men. It had two parts: first, a small test in…
This study tested whether a combination of nicotinamide (a form of vitamin B3) and pyridoxine (vitamin B6) could boost muscle stem cell activity and speed up muscle repair after intense…
This review looked at how nutrition shapes male fertility at the cellular level, focusing on how nutrients affect sperm production, function, and DNA. It pulled together human, animal, and lab…
This study looked at how high-intensity exercise and vitamin D3 supplements affect vitamin D levels differently in trained athletes versus untrained men. It compared 22 mixed martial arts athletes and…
This study set out to see whether the timing of a single dose of creatine (a well-studied supplement that helps with short, intense efforts) affects strength performance during a workout.…
This study looked at whether ashwagandha (an herbal supplement traditionally used to blunt stress) helps team-sport athletes handle the strain of pre-season training, when the stress hormone cortisol and fatigue…
This systematic review and meta-analysis set out to see whether vitamin D supplements raise testosterone or related markers in men. It pooled randomized trials measuring total testosterone, SHBG (sex hormone-binding…
This study aimed to assess how much adult men know about male fertility, focusing on medical and lifestyle factors that affect it. Researchers surveyed 156 men of reproductive age using…
This study set out to see if omega-3 (n-3 PUFA) supplements could boost muscle growth and strength gains from weight training in healthy young men already eating plenty of protein.…
This study set out to see if combining creatine (a compound stored in muscle that helps regenerate quick energy) and β-hydroxy-β-methylbutyrate (HMB, a muscle-preserving supplement) with exercise could improve mobility…
This study set out to examine whether astaxanthin (a potent antioxidant) could improve sperm quality after freezing and thawing. It pooled data from multiple studies to see how astaxanthin affected…
This study compared two forms of omega-3 supplements, structured triglycerides (STGs) and physical mixtures (PMs), to see which better boosts blood EPA levels and muscle performance. Twenty-eight healthy young men…
This study tested whether CoQ10, L-carnitine (an amino-acid-like nutrient the body uses to turn fat into energy), or both together improve semen quality in men with low sperm count, poor…
This study set out to see if taking oral medications or zinc supplements affects zinc levels in the blood and whether that links to better sperm health or fertility outcomes…
This review set out to explore how dietary fatty acids (FAs) affect sperm quality and male fertility. It looked at recent studies on how different FAs influence sperm production and…
This review looked at how oxidative stress (cell damage from unstable molecules called reactive oxygen species, a normal byproduct of metabolism that turns harmful when it outpaces the body's defenses)…
This review gathers recent evidence on what damages male fertility and how much of it can be undone. Smoking raises sperm DNA fragmentation (breaks in the genetic material inside sperm)…
This systematic review and meta-analysis set out to see whether dietary supplements improve male fertility. It pooled 50 randomised trials in which men took a supplement for at least 12…
This narrative review set out to explore how oxidative stress (an imbalance between harmful reactive oxygen species and the body's defenses) affects fertility in men and women, and whether dietary…
This study looked at whether a short, high-dose creatine (a compound stored in muscle that helps regenerate quick energy for short, hard efforts) routine improves sleep, performance, thinking, and recovery…
This study set out to test whether 8 weeks of creatine supplementation, alone or combined with ubiquinol (a form of CoQ10), could improve sperm quality in men with normal and…
This study set out to identify which factors might influence pregnancy success in couples undergoing assisted reproductive technology (ART, fertility treatments that handle eggs and sperm outside the body). It…
This review set out to examine how heavy metals like lead, mercury, and cadmium affect sperm quality and male fertility, focusing on their role in oxidative stress and antioxidant imbalance.…
This study looked at whether eating more omega-3 fatty acids (healthy fats found in fish and some plants) is linked to higher testosterone levels in men. It used data from…
This study set out to see whether ashwagandha, a herb widely sold for stress and performance, adds anything to interval training. Interval training here meant repeated hard efforts on a…
This systematic review and meta-analysis set out to assess whether coenzyme Q10 (CoQ10) supplementation improves semen quality and male hormone levels. It pooled data from eight randomized controlled trials involving…
This study looked at whether taking ZMA, a supplement combining zinc, magnesium and vitamin B6, before bed for two nights could improve sleep and next-day performance in healthy active men.…
This study set out to see whether a zinc supplement improves zinc status in healthy middle-aged American men who eat meat, a group that had not been looked at. The…
This study set out to test whether ashwagandha, a traditional herb, could reduce stress and fatigue in overweight or mildly obese adults aged 40-75 who reported high stress and fatigue.…
This study set out to see whether N-acetyl-cysteine (NAC, an antioxidant supplement, taken here at 600 mg a day) improves sperm quality in infertile men. Fifty infertile men with poor…
This meta-analysis set out to see whether omega-3 fats improve sperm in infertile men. It pooled three randomized trials, 147 men on omega-3 and 143 on control treatments, and measured…
This review pulled together what is known about how everyday life affects a man's fertility, covering age, psychological stress, nutrition, physical activity, caffeine, scrotal temperature, hot water and mobile phone…
Infertility affects about 15 percent of the world's population, which is what makes this question worth asking. This systematic review and meta-analysis pooled randomized trials testing whether nutrients, dietary supplements…
This study set out to test whether vitamin D supplements raise testosterone in healthy men. It randomly assigned 98 men with normal testosterone but low vitamin D to a high…
This study set out to see whether zinc in semen is linked to male infertility and whether zinc supplements improve sperm. It pooled 20 studies, comparing zinc levels and sperm…
This study looked at whether vitamin D levels track with testosterone, and with hypogonadism (when the testicles do not make enough testosterone, which shows up as low drive, fatigue and…
This meta-analysis set out to see if coenzyme Q10 (CoQ10) supplements improve male fertility, focusing on live birth and pregnancy rates, sperm concentration, and sperm motility. It pooled data from…
This study looked at whether magnesium supplements raise testosterone in athletes and in sedentary men, at rest and after exercising to exhaustion. Thirty healthy men aged 18 to 22 were…
This study looked at whether N-acetylcysteine (NAC), an antioxidant supplement, could improve semen quality and oxidative stress in men with unexplained infertility. It randomly assigned 120 men with idiopathic infertility…
This study looked at whether zinc levels affect testosterone in healthy men. It compared zinc levels and testosterone in 40 men aged 20 to 80, induced zinc deficiency in 4…