Clinical interventions in aging2026n = 59
CohortHuman
This study looked at how a lifetime of endurance exercise affects heart health and muscle strength in older men. It followed 59 men, average age 67, who had been doing…
American journal of physiology. Endocrinology and metabolism2026n = 12
RCTHuman
This study set out to compare how different types of exercise affect muscle metabolism and insulin sensitivity in the short term. Twelve healthy young men did three sessions: sprint intervals…
Nutrients2026n = 75 enrolled, 70 completed
RCTHuman
This study looked at whether vitamin D changes how well metformin (a common diabetes drug that lowers blood sugar) can bring down prolactin (a pituitary hormone that suppresses testosterone when…
Frontiers in endocrinology2026n = 4,269 men (7,268 records)
CohortHuman
This study looked at whether a man's TyG index tracks with his risk of low testosterone as he ages. The TyG index is a simple score figured from fasting blood…
Journal of exercise science and fitness2026n = 20
RCTHuman
This study looked at whether a quick, low-effort high-intensity interval training routine (REHIT) could improve blood sugar control after meals and over a full day in healthy, active middle-aged men.…
European journal of applied physiology2026n = 11
RCTHuman
This study set out to see if moderate-intensity walking could improve glucose tolerance after a night of partial sleep restriction, as high-intensity exercise has been shown to do. Eleven healthy,…
Gut microbes2026n = 19
RCTHuman
This study set out to see how swapping some animal protein for plant protein affects gut bacteria and tryptophan processing in men at risk for heart and metabolic problems. It…
Journal of cachexia, sarcopenia and muscle2026n = 68 (37 HIIT + L-citrulline, 31 HIIT + placebo)
RCTHuman
This study looked at how high-intensity interval training (HIIT), where short bursts of hard effort alternate with easier recovery periods, with or without L-citrulline (an amino acid that may boost…
The journal of sexual medicine2026n = 639 men across 10 studies
Systematic ReviewHuman
This systematic review set out to assess how GLP-1 receptor agonists (a class of diabetes and weight-loss drugs) affect male reproductive hormones, semen quality, and metabolic health. It pooled data…
Clinical nutrition research2026n = 4,819
Cross SectionalHuman
This study looked at whether vitamin D levels are linked to metabolic health, measured by the TyG index (a score from fasting blood sugar and triglycerides that flags insulin resistance,…
Journal of the American Heart Association2026n = 82
RCTHuman
This study looked at whether adding avocado and mango to the diet improves blood vessel function and metabolic health in adults with prediabetes. It was a randomized trial where 82…
Scientific reports2026n = 34
RCTHuman
This study compared two exercise approaches, high-intensity functional training (HIFT) and traditional resistance training (RT), for improving metabolic, inflammatory, and physical health in overweight men. Thirty-four men with an average…
Genes & nutrition2026n = 300
Case ControlHuman
This study looked at whether the quality and amount of carbohydrates in a man's diet affect sperm DNA damage, a common problem in unexplained infertility. Researchers compared 300 Iranian men…
Frontiers in physiology2026n = 369
Meta AnalysisHuman
This systematic review and meta-analysis looked at how combining aerobic exercise with other interventions affects metabolic, heart, and inflammation markers in men. It pooled data from 14 randomized controlled trials…
American journal of men's health2026n = 10,357
Cross SectionalHuman
This study looked at what drives low testosterone in U.S. men, going beyond aging to include habits and life circumstances. It analyzed over 10,000 men aged 18 and up from…
Frontiers in public health2026
Meta AnalysisHuman
This study compared two approaches to resistance training, linear periodization (a steady progression of weight up and reps down over months) and undulating periodization (varying weight and reps week to…
Journal of the International Society of Sports Nutrition2026n = 28
RCTHuman
This study compared two forms of omega-3 supplements, structured triglycerides (STGs) and physical mixtures (PMs), to see which better boosts blood EPA levels and muscle performance. Twenty-eight healthy young men…
Quantitative imaging in medicine and surgery2026n = 36
Cross SectionalHuman
This study looked at how a man's testosterone and SHBG relate to where his body stores fat. SHBG, or sex hormone-binding globulin, is a protein that binds testosterone and sets…
Asian journal of andrology2026n = 43 studies included
Systematic ReviewHuman
This umbrella review (a review of other reviews) set out to catalogue what damages male fertility. It gathered 43 systematic reviews and meta-analyses published between 2000 and 2025, covering 67…
Cureus2026
Narrative ReviewHuman
This is a narrative review (an expert summary of existing research, not a new experiment) asking whether testosterone replacement therapy (TRT) could help men with low testosterone hold onto muscle…
Andrology2025n = 200
Cross SectionalHuman
This study looked at how eating patterns relate to sperm quality in healthy young men. Researchers scored the diets of 200 men against several patterns, healthy ones like the Mediterranean…
Nutrients2025n = 106
Cross SectionalHuman
This study looked at whether dietary polyphenols (plant antioxidants found in fruits, vegetables, tea, and olive oil) are linked to semen quality in young men. It analyzed 3-day diet records…
Oncoscience2025n = 278
Cross SectionalHuman
This study looked at how lifestyle and hormones affect semen quality and sperm DNA health in men. It examined 278 Indian men aged 21 to 50, measuring sperm count, movement,…
Nutrients2025n = 358
Cross SectionalHuman
This study looked at how diet relates to sperm quality, comparing the Mediterranean diet, which is built on seasonal, fresh and whole foods, against ultra-processed foods, which are high in…
Asia Pacific journal of clinical nutrition2025n = 321
RCTHuman
This study tested whether a workplace canteen could improve the health of men with metabolic syndrome (a cluster of a large waist, high blood pressure, high blood sugar, high triglycerides,…
Nutrients2025n = 38 (20 placebo, 18 ashwagandha)
RCTHuman
This study set out to see whether ashwagandha, a herb widely sold for stress and performance, adds anything to interval training. Interval training here meant repeated hard efforts on a…
Journal of clinical medicine2024n = 73
Cross SectionalHuman
This study set out to see how lifestyle and insulin resistance relate to male fertility. Insulin resistance means the body has stopped responding properly to insulin, so it takes more…
Frontiers in endocrinology2023n = 1,222 (450 smokers, 772 non-smokers)
Cross SectionalHuman
This study set out to examine how cigarette smoking affects semen quality, hormone levels, metabolic health, zinc levels, and sperm DNA damage in young Russian men. It compared 450 smokers…
International journal of endocrinology2022n = 27,328 (7,940 with bioavailable testosterone data)
Cross SectionalHuman
This study set out to see whether testosterone in men varies with the season, independently of age, weight and existing illness. It used the medical records of 27,328 Israeli men…
The American journal of clinical nutrition2020n = 16 (8 per group)
OtherHuman
This study set out to see whether two weeks of eating earlier in the day improves how muscle takes up sugar and amino acids. Sixteen healthy young men were put…
Obesity (Silver Spring, Md.)2019n = 15
RCTHuman
This study set out to see whether restricting the hours of the day a man eats improves how his body handles sugar. Fifteen men at risk of type 2 diabetes,…
Cell metabolism2018
RCTHuman
This study set out to test whether the benefits of intermittent fasting come only from losing weight. Men with prediabetes ate all their meals inside a 6 hour window early…
The Journal of clinical endocrinology and metabolism2017n = 98
RCTHuman
This study set out to test whether vitamin D supplements raise testosterone in healthy men. It randomly assigned 98 men with normal testosterone but low vitamin D to a high…
Clinical endocrinology2015n = 19
RCTHuman
This study looked at whether catching up on sleep at the weekend improves insulin sensitivity and hormones in men who habitually sleep too little in the week. Nineteen such men…
PloS one2012n = 14
OtherHuman
This study set out to see how cutting sleep affects glucose handling and hormones in young men. Fourteen healthy men were kept in a laboratory for two nights of 10…