Clinical interventions in aging2026n = 59
CohortHuman
This study looked at how a lifetime of endurance exercise affects heart health and muscle strength in older men. It followed 59 men, average age 67, who had been doing…
Aging cell2026n = 101 men total (23 young, 57 older normal testosterone, 21 older low testosterone)
Cross SectionalHuman
This study looked at whether low testosterone in middle-aged and older men is tied to worse blood vessel health through effects on mitochondria, the tiny power plants inside cells. Researchers…
International journal of public health2026n = 22,495
CohortHuman
This study looked at whether wine drinking affects biological aging in men, using data from the Moli-sani Study in Italy. It tracked over 22,000 adults, comparing how much wine they…
Journal of cachexia, sarcopenia and muscle2026n = 68 (37 HIIT + L-citrulline, 31 HIIT + placebo)
RCTHuman
This study looked at how high-intensity interval training (HIIT), where short bursts of hard effort alternate with easier recovery periods, with or without L-citrulline (an amino acid that may boost…
Nutrients2026n = 56
RCTHuman
This study looked at whether ashwagandha (an herbal supplement traditionally used to blunt stress) helps team-sport athletes handle the strain of pre-season training, when the stress hormone cortisol and fatigue…
Clinical nutrition research2026n = 4,819
Cross SectionalHuman
This study looked at whether vitamin D levels are linked to metabolic health, measured by the TyG index (a score from fasting blood sugar and triglycerides that flags insulin resistance,…
Experimental gerontology2026n = 33
RCTHuman
This study looked at whether resistance exercise and a high-protein diet could improve metabolic flexibility (the body's ability to switch between burning carbs and fats for fuel) in older men.…
Frontiers in physiology2026
Meta AnalysisHuman
This study set out to assess how exercise affects bone mineral density (BMD) in middle-aged and older men, focusing on different skeletal sites. It pooled data from randomized controlled trials…
Journal of endocrinological investigation2026
Narrative ReviewHuman
This review looked at how aging affects men's hormones, sleep, and metabolism, centering on two kinds of hypogonadism (when the testicles do not make enough testosterone, causing symptoms like low…
Toxicology reports2026
Narrative ReviewHuman
This review set out to examine how microplastics (tiny plastic particles) affect the male reproductive system at the cellular and molecular level. It compiled findings from multiple studies across scientific…
Human reproduction (Oxford, England)2026n = 1,220
CohortHuman
Researchers followed 1,220 men at a Utah fertility clinic and matched the outdoor heat and humidity each man lived through while his sperm were forming against a molecular measure of…
Nutrients2025n = 225
Cross SectionalHuman
This study set out to explore how trace elements in the blood might relate to testosterone levels and symptoms like low energy, mood issues, and sexual health in young men.…
The journal of nutrition, health & aging2025n = 1,292 (53% women)
CohortHuman
This study looked at whether vitamin D levels in the blood are linked to developing sarcopenia (age-related muscle loss) in older adults. It followed 1,292 Korean adults aged 70-84 without…
Journal of clinical medicine2024n = 73
Cross SectionalHuman
This study set out to see how lifestyle and insulin resistance relate to male fertility. Insulin resistance means the body has stopped responding properly to insulin, so it takes more…
Andrology2024n = 1,774 participants across 44 studies
Meta AnalysisHuman
This meta-analysis set out to measure how much testosterone men with obesity get back when they lose weight, comparing low-calorie diets with bariatric surgery. It pooled 44 studies covering 1,774…
Reproductive biology and endocrinology : RB&E2023n = 190 studies
Meta AnalysisHuman
This systematic review and meta-analysis set out to find which lifestyle, environmental and health factors go with higher sperm DNA fragmentation, meaning breaks in the genetic material inside sperm, where…
Sleep2020n = 35
RCTHuman
This study set out to compare how young and older men's hormone levels respond to a night without sleep. It measured testosterone, luteinizing hormone (LH, a pituitary hormone that signals…
The Journal of nutrition2018n = 41
RCTHuman
This study set out to see if adding protein supplements after workouts and before bed would boost muscle and strength gains from weight training in older men. It compared 41…
Annals of medicine2017n = 1,663
CohortHuman
This study set out to see whether how much oxygen a man's body uses at his aerobic threshold, the point where easy effort starts to get hard, predicts his risk…
Circulation2011n = 14,345
CohortHuman
This study set out to see how changes in fitness and in body weight affect a man's risk of dying, from any cause and from heart disease. It followed 14,345…
The Journal of clinical endocrinology and metabolism2007n = 1374 at baseline, decreasing to 489 by final follow-up
CohortHuman
This study set out to measure whether testosterone in American men had fallen over calendar time, separately from the fall that comes with getting older. It drew 2769 measurements from…
The Journal of clinical endocrinology and metabolism2001n = 890
CohortHuman
This study set out to track how testosterone changes as men age, and whether the change is aging itself or the illnesses and medications that come with it. It measured…
Nutrition (Burbank, Los Angeles County, Calif.)1996n = 40 (cross-sectional), 4 (deficiency), 9 (supplementation)
OtherHuman
This study looked at whether zinc levels affect testosterone in healthy men. It compared zinc levels and testosterone in 40 men aged 20 to 80, induced zinc deficiency in 4…