Scientific reports2026
Meta AnalysisHuman
This study set out to examine whether astaxanthin (a potent antioxidant) could improve sperm quality after freezing and thawing. It pooled data from multiple studies to see how astaxanthin affected…
Toxicology reports2026
Narrative ReviewHuman
This review set out to examine how microplastics (tiny plastic particles) affect the male reproductive system at the cellular and molecular level. It compiled findings from multiple studies across scientific…
Journal of dietary supplements2025
Narrative ReviewHuman
This review set out to explore how dietary fatty acids (FAs) affect sperm quality and male fertility. It looked at recent studies on how different FAs influence sperm production and…
Nutrients2025n = 106
Cross SectionalHuman
This study looked at whether dietary polyphenols (plant antioxidants found in fruits, vegetables, tea, and olive oil) are linked to semen quality in young men. It analyzed 3-day diet records…
Antioxidants (Basel, Switzerland)2025
Narrative ReviewHuman
This review looked at how oxidative stress (cell damage from unstable molecules called reactive oxygen species, a normal byproduct of metabolism that turns harmful when it outpaces the body's defenses)…
Current opinion in urology2025
Narrative ReviewHuman
This review gathers recent evidence on what damages male fertility and how much of it can be undone. Smoking raises sperm DNA fragmentation (breaks in the genetic material inside sperm)…
Metabolites2025
Narrative ReviewHuman
This narrative review set out to explore how oxidative stress (an imbalance between harmful reactive oxygen species and the body's defenses) affects fertility in men and women, and whether dietary…
Current issues in molecular biology2025
Narrative ReviewHuman
This review set out to examine how heavy metals like lead, mercury, and cadmium affect sperm quality and male fertility, focusing on their role in oxidative stress and antioxidant imbalance.…
Journal of clinical medicine2024n = 73
Cross SectionalHuman
This study set out to see how lifestyle and insulin resistance relate to male fertility. Insulin resistance means the body has stopped responding properly to insulin, so it takes more…
Frontiers in nutrition2024n = 2032 men
Systematic ReviewHuman
This systematic review set out to assess whether following a Mediterranean diet affects sperm quality in men of reproductive age. It analyzed 10 studies involving over 2,000 men aged 18-55,…
Frontiers in pharmacology2024n = 877 (462 CoQ10-treated, 415 untreated/placebo-treated)
Meta AnalysisHuman
This systematic review and meta-analysis set out to assess whether coenzyme Q10 (CoQ10) supplementation improves semen quality and male hormone levels. It pooled data from eight randomized controlled trials involving…
Reproductive biology and endocrinology : RB&E2019n = 50
CohortHuman
This study set out to see whether N-acetyl-cysteine (NAC, an antioxidant supplement, taken here at 600 mg a day) improves sperm quality in infertile men. Fifty infertile men with poor…
Reproductive biology and endocrinology : RB&E2018
Narrative ReviewHuman
This review pulled together what is known about how everyday life affects a man's fertility, covering age, psychological stress, nutrition, physical activity, caffeine, scrotal temperature, hot water and mobile phone…
Advances in nutrition (Bethesda, Md.)2018n = 28 articles for qualitative analysis, 15 for quantitative meta-analysis
Meta AnalysisHuman
Infertility affects about 15 percent of the world's population, which is what makes this question worth asking. This systematic review and meta-analysis pooled randomized trials testing whether nutrients, dietary supplements…
Urology2009n = 120
RCTHuman
This study looked at whether N-acetylcysteine (NAC), an antioxidant supplement, could improve semen quality and oxidative stress in men with unexplained infertility. It randomly assigned 120 men with idiopathic infertility…