Cureus2026n = 4,389 eligible out of 4,601 screened
Cross SectionalHuman
This study set out to see if taking oral medications or zinc supplements affects zinc levels in the blood and whether that links to better sperm health or fertility outcomes…
Antioxidants (Basel, Switzerland)2025
Narrative ReviewHuman
This review looked at how oxidative stress (cell damage from unstable molecules called reactive oxygen species, a normal byproduct of metabolism that turns harmful when it outpaces the body's defenses)…
Metabolites2025
Narrative ReviewHuman
This narrative review set out to explore how oxidative stress (an imbalance between harmful reactive oxygen species and the body's defenses) affects fertility in men and women, and whether dietary…
Nutrients2025n = 225
Cross SectionalHuman
This study set out to explore how trace elements in the blood might relate to testosterone levels and symptoms like low energy, mood issues, and sexual health in young men.…
Journal of medical biochemistry2025n = 64 couples
Cross SectionalHuman
This study set out to identify which factors might influence pregnancy success in couples undergoing assisted reproductive technology (ART, fertility treatments that handle eggs and sperm outside the body). It…
Current issues in molecular biology2025
Narrative ReviewHuman
This review set out to examine how heavy metals like lead, mercury, and cadmium affect sperm quality and male fertility, focusing on their role in oxidative stress and antioxidant imbalance.…
Nutrients2024n = 19
OtherHuman
This study looked at whether taking ZMA, a supplement combining zinc, magnesium and vitamin B6, before bed for two nights could improve sleep and next-day performance in healthy active men.…
Nutrition and health2023
OtherHuman
This study set out to see whether a zinc supplement improves zinc status in healthy middle-aged American men who eat meat, a group that had not been looked at. The…
Frontiers in endocrinology2023n = 1,222 (450 smokers, 772 non-smokers)
Cross SectionalHuman
This study set out to examine how cigarette smoking affects semen quality, hormone levels, metabolic health, zinc levels, and sperm DNA damage in young Russian men. It compared 450 smokers…
Advances in nutrition (Bethesda, Md.)2018n = 28 articles for qualitative analysis, 15 for quantitative meta-analysis
Meta AnalysisHuman
Infertility affects about 15 percent of the world's population, which is what makes this question worth asking. This systematic review and meta-analysis pooled randomized trials testing whether nutrients, dietary supplements…
Scientific reports2016n = 2,600 cases and 867 controls
Meta AnalysisHuman
This study set out to see whether zinc in semen is linked to male infertility and whether zinc supplements improve sperm. It pooled 20 studies, comparing zinc levels and sperm…
Nutrition (Burbank, Los Angeles County, Calif.)1996n = 40 (cross-sectional), 4 (deficiency), 9 (supplementation)
OtherHuman
This study looked at whether zinc levels affect testosterone in healthy men. It compared zinc levels and testosterone in 40 men aged 20 to 80, induced zinc deficiency in 4…