Supplements

Peer-reviewed research concerning supplements, summarized and appraised in plain language with every source cited.

27Studies
27Human studies
2026Most recent
13Countries

Vitamin D Supplementation, Total Testosterone, and Androgen Bioavailability Markers in Adult Men: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Nutrients2026n = 21 comparison-level records from 18 reports

Meta AnalysisHuman

This systematic review and meta-analysis set out to see whether vitamin D supplements raise testosterone or related markers in men. It pooled randomized trials measuring total testosterone, SHBG (sex hormone-binding…

Nicotinamide and Pyridoxine Supplementation Enhances Muscle Stem Cell Activity and Muscle Regeneration in Humans: A Randomized Placebo-Controlled Clinical Trial of High Force Eccentric Contraction Recovery in Healthy Young Men.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)2026n = 39 out of 43 enrolled completed the study

RCTHuman

This study tested whether a combination of nicotinamide (a form of vitamin B3) and pyridoxine (vitamin B6) could boost muscle stem cell activity and speed up muscle repair after intense…

Combined creatine and β-hydroxy-β-methylbutyrate supplementation with integral conditioning exercise enhances functional performance and metabolic health in physically active older adults: A randomized controlled crossover trial.

Aging clinical and experimental research2026n = 30

RCTHuman

This study set out to see if combining creatine (a compound stored in muscle that helps regenerate quick energy) and β-hydroxy-β-methylbutyrate (HMB, a muscle-preserving supplement) with exercise could improve mobility…

Does coenzyme Q10 improve semen quality and circulating testosterone level? a systematic review and meta-analysis of randomized controlled trials.

Frontiers in pharmacology2024n = 877 (462 CoQ10-treated, 415 untreated/placebo-treated)

Meta AnalysisHuman

This systematic review and meta-analysis set out to assess whether coenzyme Q10 (CoQ10) supplementation improves semen quality and male hormone levels. It pooled data from eight randomized controlled trials involving…