RCTHumann = 142025Tunisia

Effects of Creatine Monohydrate Loading on Sleep Metrics, Physical Performance, Cognitive Function, and Recovery in Physically Active Men: A Randomized, Double-Blind, Placebo-Controlled, Crossover Trial.

Journal: NutrientsPublished: 2025DOI: 10.3390/nu17243831

Plain-language summary

This study looked at whether a short, high-dose creatine (a compound stored in muscle that helps regenerate quick energy for short, hard efforts) routine improves sleep, performance, thinking, and recovery in active men. Fourteen men took 20 grams of creatine monohydrate a day, or a placebo, for 7 days while keeping their usual training, with sleep and recovery tracked by a wrist motion sensor and questionnaires. Creatine improved how good their sleep felt, cut soreness, and sharpened thinking and high-intensity output, though it did not move objective sleep or recovery readings.

Key findings

  • Creatine monohydrate improved subjective sleep quality during the loading phase.
  • Creatine enhanced cognitive performance on the digit cancellation test.
  • Creatine increased total distance in the 5m shuttle run test, indicating better high-intensity performance.
  • Creatine reduced muscle soreness scores but did not affect objective sleep metrics or recovery markers beyond 72 hours.

How to analyze the study yourself

Study type
Randomized controlled trials are strong for testing cause and effect but may not reflect long-term or real-world use.
Population
Physically active men, not elite athletes or sedentary individuals.
Funding
Not reported
Watch for
This study found that a 7-day creatine load of 20 grams a day improved how well men slept, cut muscle soreness, and sharpened thinking and high-intensity output. If you want those perks, it may be worth trying a short creatine load of 20 grams daily.