Human reproduction update2026n = 32 studies included
Meta AnalysisHuman
This study set out to review how different weight loss methods affect male fertility in men with obesity. It looked at 32 studies that compared lifestyle changes, medications, and bariatric…
Scientific reports2026
Meta AnalysisHuman
This study set out to examine whether astaxanthin (a potent antioxidant) could improve sperm quality after freezing and thawing. It pooled data from multiple studies to see how astaxanthin affected…
Nutrients2025n = 50 studies included
Meta AnalysisHuman
This systematic review and meta-analysis set out to see whether dietary supplements improve male fertility. It pooled 50 randomised trials in which men took a supplement for at least 12…
Archivos espanoles de urologia2025n = 945 subjects
Meta AnalysisHuman
This study looked at whether vitamin D3 supplementation improves hormone levels and semen quality in infertile men. It pooled data from six randomized controlled trials involving 945 men, measuring changes…
Frontiers in endocrinology2025n = 8,443 men (3,467 normal BMI, 3,444 overweight, 1,532 obese)
Meta AnalysisHuman
This meta-analysis (a study that statistically pools many earlier studies) looked at how body mass index (BMI, a weight-for-height number used to flag over- or under-weight) relates to sperm quality…
Advances in nutrition (Bethesda, Md.)2025n = 2,558 individuals across 11 studies
Meta AnalysisHuman
This study set out to see if sticking to a Mediterranean diet (MedDiet) is linked to better sperm quality and fertility outcomes in men. It pooled data from 11 studies,…
Frontiers in pharmacology2024n = 877 (462 CoQ10-treated, 415 untreated/placebo-treated)
Meta AnalysisHuman
This systematic review and meta-analysis set out to assess whether coenzyme Q10 (CoQ10) supplementation improves semen quality and male hormone levels. It pooled data from eight randomized controlled trials involving…
Toxics2024n = 18 studies included
Meta AnalysisHuman
This study set out to clarify how bisphenol A (BPA, a chemical used in food packaging and container linings) affects men's reproductive health. It pooled 18 studies that measured BPA…
Reproductive biology and endocrinology : RB&E2023n = 190 studies
Meta AnalysisHuman
This systematic review and meta-analysis set out to find which lifestyle, environmental and health factors go with higher sperm DNA fragmentation, meaning breaks in the genetic material inside sperm, where…
Heliyon2023n = 40 studies
Meta AnalysisHuman
This meta-analysis set out to examine how alcohol intake affects male reproductive health by looking at semen quality, antioxidant levels in semen, sperm DNA damage, and sex hormones. It pooled…
Human reproduction update2023n = 223 studies, 288 estimates
Meta AnalysisHuman
This study set out to examine global trends in sperm count over the past several decades. It pooled data from 223 studies, including semen samples collected from men worldwide between…
Iranian journal of public health2022n = 356
Meta AnalysisHuman
This meta-analysis set out to work out how high ambient temperature affects sperm quality. It pooled nine studies covering 356 men in Iran, Italy, Thailand, China and Egypt, comparing men…
Journal of dietary supplements2019n = 290 (147 intervention, 143 control)
Meta AnalysisHuman
This meta-analysis set out to see whether omega-3 fats improve sperm in infertile men. It pooled three randomized trials, 147 men on omega-3 and 143 on control treatments, and measured…
Advances in nutrition (Bethesda, Md.)2018n = 28 articles for qualitative analysis, 15 for quantitative meta-analysis
Meta AnalysisHuman
Infertility affects about 15 percent of the world's population, which is what makes this question worth asking. This systematic review and meta-analysis pooled randomized trials testing whether nutrients, dietary supplements…
Scientific reports2016n = 2,600 cases and 867 controls
Meta AnalysisHuman
This study set out to see whether zinc in semen is linked to male infertility and whether zinc supplements improve sperm. It pooled 20 studies, comparing zinc levels and sperm…
Journal of assisted reproduction and genetics2013n = 296 (149 CoQ10, 147 placebo)
Meta AnalysisHuman
This meta-analysis set out to see if coenzyme Q10 (CoQ10) supplements improve male fertility, focusing on live birth and pregnancy rates, sperm concentration, and sperm motility. It pooled data from…