OtherHumann = 22 studies included in final evidence base2024
Updates to Male Infertility: AUA/ASRM Guideline (2024).
Plain-language summary
This 2024 update to the American Urological Association (AUA) and American Society for Reproductive Medicine (ASRM) guideline reviewed new evidence on male infertility to refine recommendations for evaluation and management. The panel screened over 4,000 new studies, selecting 22 that met their criteria to inform updates. The revised guidelines now include adjusted thresholds for genetic testing, clearer use cases for pelvic MRI in infertile men, and guidance on when to use testicular sperm (sperm taken directly from the testicle with a needle or small biopsy rather than from an ejaculated sample, because it has usually accumulated less DNA damage) in men who still have some sperm in their ejaculate.
Key findings
- Revised thresholds for Y-chromosome microdeletion testing
- New indications for pelvic MRI in infertile males
- Guidance on using testicular sperm in nonazoospermic males
How to analyze the study yourself
- Study type
- Guidelines synthesize expert consensus and the best available evidence to standardize care, but they rely on the quality and breadth of the underlying studies.
- Population
- Men with infertility
- Funding
- Not reported
- Takeaway
- This update refines when to consider genetic testing, pelvic MRI, and testicular sperm extraction for male infertility. If you're struggling to conceive, it may be worth discussing these updated diagnostic options with a fertility specialist.