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Testosterone therapy

Peer-reviewed research concerning testosterone therapy, summarized and appraised in plain language with every source cited.

5Studies

5Human studies

2026Most recent

3Countries

Effects of glucagon-like peptide-1 receptor agonists on male reproductive hormones, semen parameters, and metabolic outcomes: a systematic review.

The journal of sexual medicine2026n = 639 men across 10 studies

Systematic ReviewHuman

This systematic review set out to assess how GLP-1 receptor agonists (a class of diabetes and weight-loss drugs) affect male reproductive hormones, semen quality, and metabolic health. It pooled data…

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Individualizing Injectable Testosterone Replacement Therapy in Primary Care: Pharmacokinetics, Symptom Stability, Safety Monitoring, and Injection Frequency.

Cureus2026

Narrative ReviewHuman

This review looked at how to tailor injectable testosterone therapy for men with confirmed hypogonadism, meaning the testicles do not make enough testosterone, causing symptoms such as low libido, fatigue…

Endocrine Higher Testosterone Low Testosterone

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Testosterone Replacement Therapy as a Potential Strategy to Preserve Lean Mass in Men With Persistently Low Serum Testosterone Receiving GLP-1 Receptor Agonists: A Narrative Review.

Cureus2026

Narrative ReviewHuman

This is a narrative review (an expert summary of existing research, not a new experiment) asking whether testosterone replacement therapy (TRT) could help men with low testosterone hold onto muscle…

Endocrine GLP-1 drugs Higher Testosterone

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