Moderate Wine Consumption, Defined by the Mediterranean Diet, Is Associated With Delayed Biological Aging in Men From the Moli-sani Study.

Plain-language summary

This study looked at whether wine drinking affects biological aging in men, using data from the Moli-sani Study in Italy. It tracked over 22,000 adults, comparing how much wine they drank (from none to heavy) against their biological age, which was estimated from 36 blood markers. The study found that men who drank moderate amounts of wine, as defined by Mediterranean diet guidelines (125-500 mL per day), had slower biological aging compared to non-drinkers. The benefit peaked around 170 mL per day, while higher alcohol intake from all sources was linked to faster aging.

Key findings

• Moderate wine consumption (about 170 mL/day) was linked to slower biological aging in men.
• Heavy drinking was tied to faster biological aging.
• Overall alcohol intake (from all drinks) had no effect at moderate levels but sped aging at high doses.