Narrative ReviewHuman2026

Microplastics and male reproductive system: A comprehensive review based on cellular and molecular effects.

Journal: Toxicology reportsPublished: 2026DOI: 10.1016/j.toxrep.2026.102226

Plain-language summary

This review set out to examine how microplastics (tiny plastic particles) affect the male reproductive system at the cellular and molecular level. It compiled findings from multiple studies across scientific databases, focusing on how these particles impact testicular function, sperm production, and hormone balance. The review found that microplastics can disrupt sperm health by causing oxidative stress, inflammation, and DNA damage, and may also interfere with hormone production. The authors suggest that reducing exposure to microplastics could help protect male reproductive health.

Key findings

  • Microplastics may trigger inflammation and oxidative stress in the testicles.
  • They can damage sperm DNA and reduce sperm function and survival.
  • Microplastics may disrupt male hormone production and balance.
  • These effects could contribute to male infertility.

How to analyze the study yourself

Study type
A narrative review summarizes existing research but does not systematically pool data or assess study quality like a meta-analysis would.
Population
The review synthesized findings from various studies on microplastics and male reproductive health, but did not specify a human or animal population.
Funding
Not reported
Watch for
This review found that microplastics may harm male reproductive health by damaging sperm and disrupting hormones. While more research is needed, it may be worth reducing exposure to plastics in food and drink containers, especially if you are concerned about fertility.