Cross SectionalHumann = 64 couples2025

Factorial analysis of zinc serum levels, fatty acids, oxidative stress parameters and supplementation on assisted reproductive technology outcome.

Journal: Journal of medical biochemistryPublished: 2025DOI: 10.5937/jomb0-53112

Plain-language summary

This study set out to identify which factors might influence pregnancy success in couples undergoing assisted reproductive technology (ART, fertility treatments that handle eggs and sperm outside the body). It looked at 64 couples (both men and women) and measured things like zinc levels in semen and blood, fatty acids, oxidative stress markers, and supplement use, then linked these to ART outcomes. The study found that three main factors stood out: sperm health in men, antioxidant status in women, and supplement use (vitamin D, magnesium, and zinc) along with omega-3 and omega-6 fatty acid levels.

Key findings

  • Sperm health in men was one of the top factors linked to ART success.
  • Women's antioxidant status also played a key role.
  • Supplementing with vitamin D, magnesium, and zinc was tied to better outcomes.
  • Higher omega-3 and omega-6 fatty acid levels were linked to improved ART success.

How to analyze the study yourself

Study type
Cross-sectional studies can identify associations but cannot prove cause and effect.
Population
The study included couples undergoing ART, so findings may not apply to natural conception.
Funding
Not reported
Watch for
This study found that sperm health, antioxidant status, and supplements like vitamin D, magnesium, and zinc were linked to better ART outcomes. If you're undergoing fertility treatment, it may be worth discussing these nutrients with your doctor.